A Review on High Pressure Homoginizer

A Review on High Pressure Homoginizer

Author Name : Namrata Vairage, Atharva Tikone, Shubham Thorbole, Vaishnavi Tupe, Pratiksha Ture, Poonam Harpale, Rajesh Oswal

ABSTRACT

Homogenization is a process of achieving homogeneity throughout a product by particle size modification. It is characterized into three major categories:-ultrasonic pressure homogenization, pressure homogenization mechanical homogenizer. Applications of homogenization are diverse in food industry, chemical industry, pharmaceutical and chemical industry. Most important use of homogenization process in food industry is in milk homogenization. Selection criteria of homogenizers depend on particular application. In today’s environment, homogenizers are used to produce more consistent emulsions in a high efficiency process. A wide variety of homogenizers have been developed to run at different pressures and capacities depending on the product mixture. In addition to product improvements, today’s homogenizers also feature reduced noise and vibration and reduced maintenance. (1, 2, 11)

Dissolution testing is widely used as an analytical technique for evaluating the drug release characteristics and consistency of a pharmaceutical product. A dissolution method for any particular product, including apparatuses, speeds, and media, is developed based on the characteristics of the product. However, dissolution results from the same product using the same method can still be affected by test variables. Thus, minimizing the variance due to the system used and the operator performing the work to obtain results that distinguish changes between different dosage forms or the same dosage form from different lots is necessary.

Keywords: Homogenizer, High Pressure Homogenizer