“Synthesis, Spectroscopic Characterization ...

“Synthesis, Spectroscopic Characterization & Biological studies of Novel Class Heterocyclic Schiff Base Transition Metal Complexes

Author Name : Jitendra. N. Borase, R. G. Mahale, S. S. Rajput

ABSTRACT A novel straight forward approach to the synthesis of heterocyclic Schiff base ligand resulted from the condensation of 2, 4-dimethoxy benzaldehyde and 2-amino 4-methyl pyridine in ethanol in presence of catalytic amount of dilute HCl. Its complexes were synthesized by using metal salt or acetate results in the formation Fe (III), Co (III), Ni (II), Cu (II) respective complexes. All newly synthesized metal complexes were characterized using different physicochemical studies as elemental analysis, FT-IR, Magnetic susceptibility, Antimicrobial, Antioxidant, ESR spectrum for Copper complex in DMF solvent recorded at 77 k. The Electronic spectra and magnetic susceptibility measurements indicates that square planer and octahedral geometry of these complexes also suggest their structure in which (N, O) group acts as bidentate ligand. The thermal stability, decomposition behavior has been investigated by using thermo gravimetric analysis at heating rate 100 C per minute with nitrogen atmosphere and their thermodynamic parameter also calculated by using Freeman Carroll method. While that of data obtained from antimicrobial activity and antioxidant activity transition metal complexes show good antibacterial and antifungal activity and excellent antioxidant activity.